ORIGINAL ARTICLE
Year : 2022 | Volume
: 10 | Issue : 4 | Page : 116--123
Relationship between ABO blood group phenotypes and some cardiovascular risk factors among undergraduate students in Kano Nigeria
Isyaku Gwarzo Mukhtar, Abdulkarim Tsoho Abdullahi
Department of Human Physiology, Bayero University, Kano, Nigeria
Correspondence Address:
Dr. Isyaku Gwarzo Mukhtar
Department of Human Physiology, Bayero University, Kano
Nigeria
Background: Studies have linked ABO phenotypes to cardiovascular diseases (CVDs); however, data on the relationship between ABO phenotypes and CDV risk factors among healthy adults are lacking. Aim: To determine the relationship between ABO phenotypes and CVD risk factors among undergraduate students in Kano, Nigeria. Materials and Methods: This cross-sectional descriptive study recruited 150 participants. ABO phenotypes were determined using monoclonal antisera. Serum total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterolwere determined enzymatically, while low-density lipoprotein cholesterol (LDL-c) was calculated using the Friedewald equation. Blood pressure and anthropometric measurements were by standard protocols. Data were analyzed using SPSS version 23.0; P ≤ 0.05 was considered statistically significant. Results: Mean age of the participants was 23.12 ± 2.97 (17–31) years. The frequency of ABO phenotypes among the participants was: O (39.3%), B (26.0%), A (23.3%), and AB (11.3%). Non-O phenotypes had significantly lower systolic blood pressure (P = 0.050), higher TC (P = 0.023), TG (P = 0.003), and LDL-c (P = 0.050) compared to O phenotypes. Of the non-O phenotypes, A had significantly higher TC compared to B (P = 0.004) and O (P = 0.001); higher TG compared to O (P = 0.001); higher LDL-c compared to B (P = 0.001), AB (P = 0.042), and O (P = 0.006); heavier compared to B (P = 0.012) and O (P = 0.033); and higher hip circumference compared to B (P = 0.022). Conclusion: Non-O phenotypes, especially A phenotypes, had significantly higher mean serum lipids compared to O. ABO phenotypes should be considered in CVD risk stratification.
How to cite this article:
Mukhtar IG, Abdullahi AT. Relationship between ABO blood group phenotypes and some cardiovascular risk factors among undergraduate students in Kano Nigeria.Niger J Exp Clin Biosci 2022;10:116-123
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How to cite this URL:
Mukhtar IG, Abdullahi AT. Relationship between ABO blood group phenotypes and some cardiovascular risk factors among undergraduate students in Kano Nigeria. Niger J Exp Clin Biosci [serial online] 2022 [cited 2023 Mar 24 ];10:116-123
Available from: https://www.njecbonline.org/article.asp?issn=2348-053X;year=2022;volume=10;issue=4;spage=116;epage=123;aulast=Mukhtar;type=0 |
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