Indian Journal of Research in Homeopathy

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 9  |  Issue : 3  |  Page : 165--171

Evaluation of haematological parameters and oxidative stress-induced in rats exposed to radio-frequency radiation from mobile phones


Priscilla Ngozi Ezemelue1, D Ugochukwu Onyegbule2, Leona Chika Okoli3, Kafilat Olaide Kareem4, Olufunsho Awodele5, Adebayo Akeem Otitoloju1 
1 Department of Zoology, Faculty of Science, University of Lagos, Lagos, Nigeria
2 Department of Chemical Engineering, Faculty of Engineering, Technology, Fed. Polytechnic, Auchi, Edo, Nigeria
3 Center for Human Virology, Genomics and Laboratory, Nigerian Institute of Medical Research, Lagos, Nigeria
4 Department of Biochemistry, Nigerian Institute of Medical Research, Lagos, Nigeria
5 Department of Pharmacology, College of Medicine, University of Lagos, Lagos, Nigeria

Correspondence Address:
Dr. Priscilla Ngozi Ezemelue
Nigerian Institute of Medical Research, 6 Edmund Crescent Yaba, Lagos
Nigeria

Introduction: The use of new wireless technologies emitting radio-frequency electromagnetic field (RF-EMF) radiation has been introduced worldwide, raising concerns about their biosafety. So far, there have been contradictory scientific reports which have led to active debates over the bio-effects of EMF on the ecosystem. Aim: This study, therefore, aims to evaluate the bio-effect of exposure to RF-EMF from a mobile phone simulator. Materials and Methods: The experimental study used 16 healthy albino rats (8 females/8 males) randomly selected and divided equally into two groups: Group A (8 rats exposed to mobile phone simulators) and Group C (8 rats as control); the study procedure was carried out for 6 weeks. The rats were examined for physical changes, hematological profiles, and serum oxidative stress (OS) biomarkers. Results: The outcome of the study showed that exposure to RF-EMF affected the weight of the animals; this is illustrated when comparing the baseline weight/final weight of the exposed as compared to the control. This trend was also replicated when compared across gender, though further analysis showed no significance across the two groups (P > 0.05). The result of the hematological analysis showed that only granulocytes (neutrophils, basophils, and eosinophils) showed significance (P = 0.04), while for OS biomarkers, the result showed that superoxide dismutase and catalase showed significant difference (P = 0.02), respectively, across the two groups. Conclusion: This study concludes that exposure to RF-EMF has an associated effect on hematology and OS induction and therefore recommends the adherence to the precautionary principle while further research has been carried out on their specific mechanism and site of action.


How to cite this article:
Ezemelue PN, Onyegbule D U, Okoli LC, Kareem KO, Awodele O, Otitoloju AA. Evaluation of haematological parameters and oxidative stress-induced in rats exposed to radio-frequency radiation from mobile phones.Niger J Exp Clin Biosci 2021;9:165-171


How to cite this URL:
Ezemelue PN, Onyegbule D U, Okoli LC, Kareem KO, Awodele O, Otitoloju AA. Evaluation of haematological parameters and oxidative stress-induced in rats exposed to radio-frequency radiation from mobile phones. Niger J Exp Clin Biosci [serial online] 2021 [cited 2022 May 25 ];9:165-171
Available from: https://www.njecbonline.org/article.asp?issn=2348-053X;year=2021;volume=9;issue=3;spage=165;epage=171;aulast=Ezemelue;type=0