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Year : 2013  |  Volume : 1  |  Issue : 1  |  Page : 53-54

Protagonist role of oral atropine in the subacute phase of organophosphate poisoning

1 Department of Paediatrics, Columbia Asia Hospital, Ghaziabad, India
2 Paediatrician, Columbia Asia Hospital, Ghaziabad, India
3 Department of Paediatrics, RLJ Hospital, Sri Devraj Urs Medical College, Kolar, Karnataka, India
4 Department of Biochemistry, Scientific Research Laboratory-AHS, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India

Correspondence Address:
Pradeep Kumar Vegi
Research Scientist, Proteomics, Central Research Laboratory, Cell Biology and Molecular Genetics, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka - 563 101
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Source of Support: Columbia Asia Hospital and Sri Devaraj Urs Academy of Higher Education and Research, Conflict of Interest: None

DOI: 10.4103/2348-0149.123966

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Organophosphates (OPs) are widely used as insecticides. Accidental OP poisoning is reported world over. These compounds inhibit the enzyme acetylcholinesterase within the peripheral and central nervous system by phosphorylation of its esteratic site. The resultant accumulation of acetylcholine at the cholinergic receptor sites, leads to signs of cholinergic toxicity. Accidental OP ingestion has rarely been reported in young toddlers. We report a case of acute OP poisoning (dichlorvos) in an 18-month-old boy with special reference to use of oral atropine treatment in subacute phase.

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